home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Software Vault: The Sapphire Collection
/
Software Vault (Sapphire Collection) (Digital Impact).ISO
/
cdr16
/
med9410d.zip
/
M94A0676.TXT
< prev
next >
Wrap
Text File
|
1994-10-21
|
2KB
|
39 lines
Document 0676
DOCN M94A0676
TI HIV infection in recipients of blood products from donors with
identified dates of HIV seroconversion.
DT 9412
AU Ashton L; Learmont J; Luo K; Wylie B; Stewart G; Kaldor J; National
Centre for HIV Epidemiology and Clinical Research,; Sydney.
SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:44 (abstract no. FE3).
Unique Identifier : AIDSLINE ASHM5/94348979
AB OBJECTIVES: To study factors that influence survival time in
HIV-infected transfusion recipients. METHODS: A registry of people with
transfusion acquired HIV infection (TAHIV) in NSW was established by the
Red Cross Blood Transfusion Service; annual follow-up was implemented in
1990. From the registry a group of 6 donors were identified for whom
approximate seroconversion dates could be established. Survival analysis
was performed for the 25 corresponding recipients using the log rank
test and Cox proportional hazards regression. RESULTS: Three factors
were found to be significantly associated with increased survival rates
in univariate and multivariate analyses. Recipients who received blood
from donors who did not develop AIDS within 10 years appeared to survive
significantly longer than recipients who received blood from donors who
did (p = 0.01). Recipients aged under 50 years of age had significantly
longer survival times than recipients aged over 50 (p < 0.01) and the
number of transfusions was found to be inversely associated with
survival (p < 0.01). Gender, zidovudine treatment and severity of
illness at transfusion were not found to be significantly associated
with survival time. CONCLUSION: Age, disease progression in the donor
and the number of transfusions appeared to be important predictors of
survival in people with TAHIV.
DE Adult Australia/EPIDEMIOLOGY Blood Donors/*STATISTICS & NUMER DATA
Blood Transfusion/*MORTALITY Cause of Death Female Follow-Up Studies
Human HIV Infections/MORTALITY/*TRANSMISSION HIV
Seropositivity/MORTALITY/*TRANSMISSION Male Middle Age Proportional
Hazards Models Survival Rate MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).